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GROWTH DIFFERENTIATION FACTOR 3
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DeCS
Descriptor
English
:
Growth Differentiation Factor 3
Descriptor
Spanish
:
Factor 3 de Diferenciación de Crecimiento
Descriptor
Portuguese
:
Fator 3 de Diferenciação de Crescimento
Synonyms
English
:
GDF-3
Tree Number:
D12.644.276.954.300.300
D12.644.276.954.550.300
D12.776.467.942.300.300
D12.776.467.942.550.300
D23.529.942.300.300
D23.529.942.550.300
Definition
English
:
A
growth
differentiation factor that may play a role in maintaining the undifferentiated state of
PLURIPOTENT STEM CELLS
by inhibiting the actions of
BONE MORPHOGENETIC PROTEINS
. Differentiation factor 3 is also considered a nodal signaling ligand that influences the genesis of left-right asymmetry.
History Note
English
:
2009(1993)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
53140
Unique Identifier:
D055451
Occurrence in VHL
:
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CID-10
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